Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F–DP

The E2F and DP protein families form heterodimeric transcription factors that play a central role in the expression of cell cycle-regulated genes. The crystal structure of an E2F4–DP2–DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-hel...

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Publié dans:	Genes Dev
Auteurs principaux:	Zheng, Ning, Fraenkel, Ernest, Pabo, Carl O., Pavletich, Nikola P.
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 1999
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10090723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.6.666
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