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New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2

The POU transcription factor Oct-4 is expressed specifically in the germ line, pluripotent cells of the pregastrulation embryo and stem cell lines derived from the early embryo. Osteopontin (OPN) is a protein secreted by cells of the preimplantation embryo and contains a GRGDS motif that can bind to...

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Detalhes bibliográficos
Main Authors: Botquin, Valérie, Hess, Heike, Fuhrmann, Guy, Anastassiadis, Constantinos, Gross, Michael K., Vriend, Gerrit, Schöler, Hans R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316977/
https://ncbi.nlm.nih.gov/pubmed/9649510
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