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Evaluation of the Safety and Immunogenicity in Rhesus Monkeys of a Recombinant Malaria Vaccine for Plasmodium vivax with a Synthetic Toll-Like Receptor 4 Agonist Formulated in an Emulsion

Plasmodium vivax is the major cause of malaria outside sub-Saharan Africa and inflicts debilitating morbidity and consequent economic impacts in developing countries. In order to produce a P. vivax vaccine for global use, we have previously reported the development of a novel chimeric recombinant pr...

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Main Authors: Lumsden, Joanne M., Pichyangkul, Sathit, Srichairatanakul, Utaiwan, Yongvanitchit, Kosol, Limsalakpetch, Amporn, Nurmukhambetova, Saule, Klein, Jennifer, Bertholet, Sylvie, Vedvick, Thomas S., Reed, Steven G., Sattabongkot, Jetsumon, Bennett, Jason W., Polhemus, Mark E., Ockenhouse, Christian F., Howard, Randall F., Yadava, Anjali
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2011
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165477/
https://ncbi.nlm.nih.gov/pubmed/21690242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05257-11
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