Evaluation of the Safety and Immunogenicity in Rhesus Monkeys of a Recombinant Malaria Vaccine for Plasmodium vivax with a Synthetic Toll-Like Receptor 4 Agonist Formulated in an Emulsion

Plasmodium vivax is the major cause of malaria outside sub-Saharan Africa and inflicts debilitating morbidity and consequent economic impacts in developing countries. In order to produce a P. vivax vaccine for global use, we have previously reported the development of a novel chimeric recombinant pr...

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Detalhes bibliográficos
Main Authors: Lumsden, Joanne M., Pichyangkul, Sathit, Srichairatanakul, Utaiwan, Yongvanitchit, Kosol, Limsalakpetch, Amporn, Nurmukhambetova, Saule, Klein, Jennifer, Bertholet, Sylvie, Vedvick, Thomas S., Reed, Steven G., Sattabongkot, Jetsumon, Bennett, Jason W., Polhemus, Mark E., Ockenhouse, Christian F., Howard, Randall F., Yadava, Anjali
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165477/
https://ncbi.nlm.nih.gov/pubmed/21690242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05257-11
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