Cholesterol Depletion Reduces Entry of Campylobacter jejuni Cytolethal Distending Toxin and Attenuates Intoxication of Host Cells

Campylobacter jejuni is a common cause of pediatric diarrhea worldwide. Cytolethal distending toxin, produced by Campylobacter jejuni, is a putative virulence factor that induces cell cycle arrest and apoptosis in eukaryotic cells. Cellular cholesterol, a major component of lipid rafts, has a pivota...

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Main Authors: Lin, Chia-Der, Lai, Cheng-Kuo, Lin, Yu-Hsin, Hsieh, Jer-Tsong, Sing, Yu-Ting, Chang, Yun-Chieh, Chen, Kai-Chuan, Wang, Wen-Ching, Su, Hong-Lin, Lai, Chih-Ho
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165462/
https://ncbi.nlm.nih.gov/pubmed/21730089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05175-11
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