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Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1

The overexpression of the MDR1 gene, which encodes a multidrug efflux pump of the major facilitator superfamily, is a frequent cause of resistance to the widely used antimycotic agent fluconazole and other toxic compounds in the pathogenic yeast Candida albicans. The zinc cluster transcription facto...

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Detalhes bibliográficos
Main Authors: Schubert, Sabrina, Popp, Christina, Rogers, P. David, Morschhäuser, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165443/
https://ncbi.nlm.nih.gov/pubmed/21685320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05100-11
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