A High-Throughput Screening Assay for Inhibitors of Bacterial Motility Identifies a Novel Inhibitor of the Na(+)-Driven Flagellar Motor and Virulence Gene Expression in Vibrio cholerae

Numerous bacterial pathogens, particularly those that colonize fast-flow areas in the bladder and gastrointestinal tract, require motility to establish infection and spread beyond the initially colonized tissue. Vibrio cholerae strains of serogroups O1 and O139, the causative agents of the diarrheal...

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Bibliographic Details
Main Authors: Rasmussen, Lynn, White, E. Lucile, Pathak, Ashish, Ayala, Julio C., Wang, Hongxia, Wu, Jian-He, Benitez, Jorge A., Silva, Anisia J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Analytical Procedures
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165335/
https://ncbi.nlm.nih.gov/pubmed/21709090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00482-11
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