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A Vibrio cholerae Relaxed (relA) Mutant Expresses Major Virulence Factors, Exhibits Biofilm Formation and Motility, and Colonizes the Suckling Mouse Intestine

We have constructed a relaxed mutant of El Tor biotype Vibrio cholerae strain C7258 by disruption of the RelA catalytic domain. The ability of the V. cholerae relaxed mutant to biosynthesize guanosine tetraphosphate and pentaphosphate was severely affected; the mutant showed a reduced growth rate in...

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Detalhes bibliográficos
Main Authors: Silva, Anisia J., Benitez, Jorge A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347285/
https://ncbi.nlm.nih.gov/pubmed/16385069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.2.794-800.2006
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