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Recombinant Phenotyping of Cytomegalovirus UL54 Mutations That Emerged during Cell Passages in the Presence of either Ganciclovir or Foscarnet

Selection of human cytomegalovirus variants in the presence of ganciclovir or foscarnet led to 18 DNA polymerase mutations, 14 of which had not been previously studied. Using bacterial artificial chromosome technology, each of these mutations was individually transferred into the genome of a referen...

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Detalhes bibliográficos
Main Authors: Gilbert, Christian, Azzi, Arezki, Goyette, Nathalie, Lin, Sheng-Xiang, Boivin, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165324/
https://ncbi.nlm.nih.gov/pubmed/21709106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00334-11
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