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A Small Amount of Fat Does Not Affect Piperaquine Exposure in Patients with Malaria

Dihydroartemisinin-piperaquine is a new, highly effective, and well-tolerated combination treatment for uncomplicated falciparum malaria. The lipophilic characteristic of piperaquine suggests that administration together with fat will increase the oral bioavailability of the drug, and this has been...

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Detalhes bibliográficos
Main Authors: Annerberg, Anna, Lwin, Khin Maung, Lindegardh, Niklas, Khrutsawadchai, Sakchai, Ashley, Elizabeth, Day, Nicholas P. J., Singhasivanon, Pratap, Tarning, Joel, White, Nicholas J., Nosten, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165307/
https://ncbi.nlm.nih.gov/pubmed/21709087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00279-11
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