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Mapping the Substrate Binding Site of Phenylacetone Monooxygenase from Thermobifida fusca by Mutational Analysis

Baeyer-Villiger monooxygenases catalyze oxidations that are of interest for biocatalytic applications. Among these enzymes, phenylacetone monooxygenase (PAMO) from Thermobifida fusca is the only protein showing remarkable stability. While related enzymes often present a broad substrate scope, PAMO a...

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Détails bibliographiques
Auteurs principaux: Dudek, Hanna M., de Gonzalo, Gonzalo, Torres Pazmiño, Daniel E., Stępniak, Piotr, Wyrwicz, Lucjan S., Rychlewski, Leszek, Fraaije, Marco W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165276/
https://ncbi.nlm.nih.gov/pubmed/21724896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00687-11
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