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THE RON RECEPTOR PROMOTES PROSTATE TUMOR GROWTH IN THE TRAMP MOUSE MODEL

The Ron receptor tyrosine kinase is overexpressed in many cancers, including prostate cancer. In order to examine the significance of Ron in prostate cancer in vivo, we utilized a genetically engineered mouse model, referred to as TRAMP mice, that is predisposed to develop prostate tumors. In this m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thobe, Megan N., Gray, Jerilyn K., Gurusamy, Devikala, Paluch, Andrew M., Wagh, Purnima K., Pathrose, Peterson, Lentsch, Alex B., Waltz, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165145/
https://ncbi.nlm.nih.gov/pubmed/21625214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.205
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