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Improving Aptamer Selection Efficiency through Volume Dilution, Magnetic Concentration, and Continuous Washing in Microfluidic Channels

The generation of nucleic acid aptamers with high affinity typically entails a time-consuming, iterative process of binding, separation, and amplification. It would therefore be beneficial to develop an efficient selection strategy that can generate these high quality aptamers rapidly, economically,...

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מידע ביבליוגרפי
Main Authors: Oh, Seung Soo, Ahmad, Kareem M., Cho, Minseon, Kim, Seon, Xiao, Yi, Soh, H. Tom
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165111/
https://ncbi.nlm.nih.gov/pubmed/21774453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201269f
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