The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

Chromosome segregation depends on kinetochores, the structures that mediate chromosome attachment to the mitotic spindle. We isolated mutants in IPL1, which encodes a protein kinase, in a screen for budding yeast mutants that have defects in sister chromatid separation and segregation. Cytological t...

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Bibliographic Details
Main Authors: Biggins, Sue, Severin, Fedor F., Bhalla, Needhi, Sassoon, Ingrid, Hyman, Anthony A., Murray, Andrew W.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316509/
https://ncbi.nlm.nih.gov/pubmed/10072382
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