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Transmission distortion in Crohn’s disease risk gene ATG16L1 leads to sex difference in disease association

BACKGROUND: Crohn’s disease (CD), an inflammatory disease of the bowel, affects millions of people around the world. Evidence suggests that disease onset and pathogenesis differ between males and females. Yet no comprehensive efforts exist to assess the sex-specific genetic architecture of CD. METHO...

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Main Authors: Liu, Linda Y., Schaub, Marc A., Sirota, Marina, Butte, Atul J.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165065/
https://ncbi.nlm.nih.gov/pubmed/21618365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21781
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