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Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

The E2F transcription factor plays a pivotal role in the timely activation of gene expression during mammalian cell cycle progression, whereas pRB and related proteins control cell growth in part through the ability to block the action of E2F. To identify physiologically important E2F-responsive pro...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Takahashi, Yasuhiko, Rayman, Joseph B., Dynlacht, Brian David
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316494/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10766737/
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