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A Galectin-3 Sequence Polymorphism Confers TRAIL Sensitivity to Human Breast Cancer Cells

BACKGROUND: A common polymorphism, rs4644, coding for Pro64 or His 64 of the carbohydrate-binding protein galectin-3, influences susceptibility of galectin-3 to cleavage by matrix metalloproteinases and is associated with breast cancer incidence. Since forced expression of galectin-3 in a galectin-3...

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Detalhes bibliográficos
Main Authors: Mazurek, Nachman, Byrd, James C., Sun, Yunjie, Ueno, Suguru, Bresalier, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164935/
https://ncbi.nlm.nih.gov/pubmed/21446041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26078
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