Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity

Cdk7 has been shown previously to be able to phosphorylate and activate many different Cdks in vitro. However, conclusive evidence that Cdk7 acts as a Cdk-activating kinase (CAK) in vivo has remained elusive. Adding to the controversy is the fact that in the budding yeast Saccharomyces cerevisiae, C...

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הוצא לאור ב:	Genes Dev
Principais autores:	Larochelle, Stéphane, Pandur, Judit, Fisher, Robert P., Salz, Helen K., Suter, Beat
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Cold Spring Harbor Laboratory Press 1998
נושאים:	Research Paper
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9450931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.3.370
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