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Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity

Cdk7 has been shown previously to be able to phosphorylate and activate many different Cdks in vitro. However, conclusive evidence that Cdk7 acts as a Cdk-activating kinase (CAK) in vivo has remained elusive. Adding to the controversy is the fact that in the budding yeast Saccharomyces cerevisiae, C...

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Auteurs principaux: Larochelle, Stéphane, Pandur, Judit, Fisher, Robert P., Salz, Helen K., Suter, Beat
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316490/
https://ncbi.nlm.nih.gov/pubmed/9450931
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