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Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers

Transparency of the ocular lens depends on symmetric packing and membrane organization of highly elongated hexagonal fiber cells. These cells possess an extensive, well-ordered cortical cytoskeleton to maintain cell shape and to anchor membrane components. Periaxin (Prx), a PDZ domain protein involv...

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Detalhes bibliográficos
Main Authors: Maddala, Rupalatha, Skiba, Nikolai P., Lalane, Robert, Sherman, Diane L., Brophy, Peter J., Rao, Ponugoti V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164832/
https://ncbi.nlm.nih.gov/pubmed/21745462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.06.036
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