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Genome-Scale Analysis of Translation Elongation with a Ribosome Flow Model

We describe the first large scale analysis of gene translation that is based on a model that takes into account the physical and dynamical nature of this process. The Ribosomal Flow Model (RFM) predicts fundamental features of the translation process, including translation rates, protein abundance l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reuveni, Shlomi, Meilijson, Isaac, Kupiec, Martin, Ruppin, Eytan, Tuller, Tamir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164701/
https://ncbi.nlm.nih.gov/pubmed/21909250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002127
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