Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor

Splicing of certain pre-mRNA introns is dependent on an enhancer element, which is typically purine-rich. It is generally thought that enhancers increase the use of suboptimal splicing signals, and one specific proposal is that enhancers stabilize binding of U2AF(65) to weak polypyrimidine (Py) trac...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Kan, Julie L.C., Green, Michael R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 1999
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.462
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