Bmp4 is required for the generation of primordial germ cells in the mouse embryo

In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited in the egg. However, in mammals, inductive cell interactions are required around gastrulation to establish the germ line. Here, we show that Bmp4 homozygous null embryos co...

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Autores principales: Lawson, Kirstie A., Dunn, N. Ray, Roelen, Bernard A.J., Zeinstra, Laura M., Davis, Angela M., Wright, Christopher V.E., Korving, Jeroen P.W.F.M., Hogan, Brigid L.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC316469/
https://ncbi.nlm.nih.gov/pubmed/10049358
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