Impairment of Immunoproteasome Function by β5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis

Proteasomes recognize and degrade poly-ubiquitinylated proteins. In infectious disease, cells activated by interferons (IFNs) express three unique catalytic subunits β1i/LMP2, β2i/MECL-1 and β5i/LMP7 forming an alternative proteasome isoform, the immunoproteasome (IP). The in vivo function of IPs in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Opitz, Elisa, Koch, Annett, Klingel, Karin, Schmidt, Frank, Prokop, Stefan, Rahnefeld, Anna, Sauter, Martina, Heppner, Frank L., Völker, Uwe, Kandolf, Reinhard, Kuckelkorn, Ulrike, Stangl, Karl, Krüger, Elke, Kloetzel, Peter M., Voigt, Antje
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164653/
https://ncbi.nlm.nih.gov/pubmed/21909276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002233
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker