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The zinc ribbon domains of the general transcription factors TFIIB and Brf: conserved functional surfaces but different roles in transcription initiation

The function of the conserved zinc-binding domains in the related Pol II- and Pol III-specific factors TFIIB and Brf was investigated. Three-dimensional structure modeling and mutagenesis studies indicated that for both factors, the functional surface of the zinc ribbon fold consists of a small cons...

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Библиографические подробности
Главные авторы: Hahn, Steven, Roberts, Sadia
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC316465/
https://ncbi.nlm.nih.gov/pubmed/10733531
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