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Discovering and validating unknown phospho-sites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools

BACKGROUND: The mitogen activated protein kinase (MAPK) pathways are known to be deregulated in many human malignancies. Phosphopeptide identification of protein-kinases and site determination are major challenges in biomedical mass spectrometry (MS). P38 and HuR protein kinases have been reported e...

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Detalhes bibliográficos
Main Authors: López, Elena, López, Isabel, Sequí, Julia, Ferreira, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164609/
https://ncbi.nlm.nih.gov/pubmed/21884634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2043-9113-1-16
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