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E2f3 is critical for normal cellular proliferation

E2F is a family of transcription factors that regulate both cellular proliferation and differentiation. To establish the role of E2F3 in vivo, we generated an E2f3 mutant mouse strain. E2F3-deficient mice arise at one-quarter of the expected frequency, demonstrating that E2F3 is important for normal...

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Detalhes bibliográficos
Main Authors: Humbert, Patrick O., Verona, Raluca, Trimarchi, Jeffrey M., Rogers, Catherine, Dandapani, Savita, Lees, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316459/
https://ncbi.nlm.nih.gov/pubmed/10733529
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