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RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis

RhoGTPases are key signaling molecules regulating main cellular functions such as migration, proliferation, survival, and gene expression through interactions with various effectors. Within the RhoA-related subclass, RhoA and RhoC contribute to several steps of tumor growth, and the regulation of th...

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Bibliographic Details
Main Authors: Giang Ho, T. T., Stultiens, Audrey, Dubail, Johanne, Lapière, Charles M., Nusgens, Betty V., Colige, Alain C., Deroanne, Christophe F.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164471/
https://ncbi.nlm.nih.gov/pubmed/21757538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0020
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