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RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis

RhoGTPases are key signaling molecules regulating main cellular functions such as migration, proliferation, survival, and gene expression through interactions with various effectors. Within the RhoA-related subclass, RhoA and RhoC contribute to several steps of tumor growth, and the regulation of th...

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Autors principals: Giang Ho, T. T., Stultiens, Audrey, Dubail, Johanne, Lapière, Charles M., Nusgens, Betty V., Colige, Alain C., Deroanne, Christophe F.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164471/
https://ncbi.nlm.nih.gov/pubmed/21757538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0020
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