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Podosome rings generate forces that drive saltatory osteoclast migration

Podosomes are dynamic, actin-containing adhesion structures that collectively self-organize as rings. In this study, we first show by observing osteoclasts plated on bead-seeded soft substrates that podosome assemblies, such as rings, are involved in tension forces. During the expansion of a podosom...

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Bibliographic Details
Main Authors: Hu, Shiqiong, Planus, Emmanuelle, Georgess, Dan, Place, Christophe, Wang, Xianghui, Albiges-Rizo, Corinne, Jurdic, Pierre, Géminard, Jean-Christophe
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164459/
https://ncbi.nlm.nih.gov/pubmed/21737683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0086
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