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Nuclear lipid microdomains regulate nuclear vitamin D(3) uptake and influence embryonic hippocampal cell differentiation
Despite recent advances in the understanding of the role of 1,25-dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)) in the CNS, the mechanism of action remains obscure. We demonstrate that some 1,25-(OH)(2)D(3) receptor (VDR) is localized in the cell nucleus in specialized microdomains enriched in sphingomyel...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164451/ https://ncbi.nlm.nih.gov/pubmed/21737687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0196 |
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