Nuclear lipid microdomains regulate nuclear vitamin D(3) uptake and influence embryonic hippocampal cell differentiation

Despite recent advances in the understanding of the role of 1,25-dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)) in the CNS, the mechanism of action remains obscure. We demonstrate that some 1,25-(OH)(2)D(3) receptor (VDR) is localized in the cell nucleus in specialized microdomains enriched in sphingomyel...

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Autores principales: Bartoccini, Elisa, Marini, Francesca, Damaskopoulou, Eleni, Lazzarini, Remo, Cataldi, Samuela, Cascianelli, Giacomo, Gil Garcia, Mercedes, Albi, Elisabetta
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164451/
https://ncbi.nlm.nih.gov/pubmed/21737687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0196
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