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Lowering the Threshold of Lung Innate Immune Cell Activation Alters Susceptibility to Secondary Bacterial Superinfection

Background. Previous studies have shown that the interaction of CD200R, a myeloid inhibitory receptor, with its ligand, CD200, is critical in the control of innate immune activation in the lung. Methods and Results. Using a mouse model of bacterial superinfection following influenza, we show that an...

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Main Authors: Goulding, John, Godlee, Alexandra, Vekaria, Seema, Hilty, Markus, Snelgrove, Robert, Hussell, Tracy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164429/
https://ncbi.nlm.nih.gov/pubmed/21881124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir467
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