Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

The reason why severe localized or systemic virus infections enhance and aggravate bacterial superinfection is poorly understood. Here we show that virus-induced IFN type I caused apoptosis in bone marrow granulocytes, drastically reduced granulocyte infiltrates at the site of bacterial superinfecti...

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Detalhes bibliográficos
Main Authors: Navarini, Alexander A., Recher, Mike, Lang, Karl S., Georgiev, Panco, Meury, Susanne, Bergthaler, Andreas, Flatz, Lukas, Bille, Jacques, Landmann, Regine, Odermatt, Bernhard, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622858/
https://ncbi.nlm.nih.gov/pubmed/17030789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607325103
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