Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

The liver is known to be a classical immunoprivileged site with a relatively high resistance against immune responses. Here we demonstrate that highly activated liver-specific effector CD8(+) T cells alone were not sufficient to trigger immune destruction of the liver in mice. Only additional innate...

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Detalhes bibliográficos
Main Authors: Lang, Karl S., Georgiev, Panco, Recher, Mike, Navarini, Alexander A., Bergthaler, Andreas, Heikenwalder, Mathias, Harris, Nicola L., Junt, Tobias, Odermatt, Bernhard, Clavien, Pierre-Alain, Pircher, Hanspeter, Akira, Shizuo, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555644/
https://ncbi.nlm.nih.gov/pubmed/16955143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28349
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