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PTEN reconstitution alters glioma responses to C-Met pathway inhibition
Mutations/deletions of the tumor suppressor phosphatase and tensin homolog PTEN, results in PI3K/Akt pathway hyperactivation and potentially alters oncogenic responses to targeted receptor tyrosine kinase inhibitors. We previously showed that hepatocyte growth factor (HGF):c-Met pathway inhibition d...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164392/ https://ncbi.nlm.nih.gov/pubmed/21654317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283484750 |
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