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Retinoic Acid Isomers Up-Regulate ATP Binding Cassette A1 and G1 and Cholesterol Efflux in Rat Astrocytes: Implications for Their Therapeutic and Teratogenic Effects

Recent studies suggest that retinoids may be effective in the treatment of Alzheimer's disease, although exposure to an excess of retinoids during gestation causes teratogenesis. Cholesterol is essential for brain development, but high levels of cholesterol have been associated with Alzheimer&#...

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Main Authors: Chen, Jing, Costa, Lucio G., Guizzetti, Marina
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164352/
https://ncbi.nlm.nih.gov/pubmed/21628419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.182196
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