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Calcium/Calmodulin-Dependent Kinase II Mediates the Phosphorylation and Activation of NADPH Oxidase 5

Excessive synthesis of reactive oxygen species contributes to the pathology of many human diseases and originates from changes in the expression and posttranslational regulation of the transmembrane NADPH oxidases (Noxes). Nox5 is a novel Nox isoform whose activity is regulated by intracellular calc...

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Autori principali: Pandey, Deepesh, Gratton, Jean-Philippe, Rafikov, Ruslan, Black, Stephen M., Fulton, David J. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164331/
https://ncbi.nlm.nih.gov/pubmed/21642394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070193
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