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Calcium/Calmodulin-Dependent Kinase II Mediates the Phosphorylation and Activation of NADPH Oxidase 5

Excessive synthesis of reactive oxygen species contributes to the pathology of many human diseases and originates from changes in the expression and posttranslational regulation of the transmembrane NADPH oxidases (Noxes). Nox5 is a novel Nox isoform whose activity is regulated by intracellular calc...

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Main Authors: Pandey, Deepesh, Gratton, Jean-Philippe, Rafikov, Ruslan, Black, Stephen M., Fulton, David J. R.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164331/
https://ncbi.nlm.nih.gov/pubmed/21642394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070193
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