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The potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: Examining the RV144 trial results

BACKGROUND: The prime-boost HIV vaccine regimen used in the recent RV144 trial resulted in modest efficacy of 31% over 3.5 years, but was substantially higher in the first year post-vaccination. We sought to explore the potential impact of a vaccine with rapidly waning efficacy in a South African po...

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Библиографические подробности
Главные авторы: Andersson, Kyeen M., Paltiel, A. David, Owens, Douglas K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164284/
https://ncbi.nlm.nih.gov/pubmed/21736912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.06.076
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