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Differential Mechanical Stability of Filamin A Rod Segments

Prompted by recent reports suggesting that interaction of filamin A (FLNa) with its binding partners is regulated by mechanical force, we examined mechanical properties of FLNa domains using magnetic tweezers. FLNa, an actin cross-linking protein, consists of two subunits that dimerize through a C-t...

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Main Authors: Chen, Hu, Zhu, Xiaoying, Cong, Peiwen, Sheetz, Michael P., Nakamura, Fumihiko, Yan, Jie
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164173/
https://ncbi.nlm.nih.gov/pubmed/21889461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.028
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