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Spontaneous Contractility-Mediated Cortical Flow Generates Cell Migration in Three-Dimensional Environments

We present a model of cell motility generated by actomyosin contraction of the cell cortex. We identify, analytically, dynamical instabilities of the cortex and show that they yield steady-state cortical flows, which, in turn, can induce cell migration in three-dimensional environments. This mechani...

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Detalhes bibliográficos
Main Authors: Hawkins, Rhoda J., Poincloux, Renaud, Bénichou, Olivier, Piel, Matthieu, Chavrier, Philippe, Voituriez, Raphaël
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164128/
https://ncbi.nlm.nih.gov/pubmed/21889440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.038
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