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Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel

Cancer cells use different modes of migration, including integrin-dependent mesenchymal migration of elongated cells along elements of the 3D matrix as opposed to low-adhesion-, contraction-based amoeboid motility of rounded cells. We report that MDA-MB-231 human breast adenocarcinoma cells invade 3...

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Detalhes bibliográficos
Main Authors: Poincloux, Renaud, Collin, Olivier, Lizárraga, Floria, Romao, Maryse, Debray, Marcel, Piel, Matthieu, Chavrier, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033302/
https://ncbi.nlm.nih.gov/pubmed/21245302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010396108
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