Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia

Growth factor Neuregulin 1 (NRG1) plays an essential role in development and organization of the cerebral cortex. NRG1 and its receptors, ERBB3 and ERBB4, have been implicated in genetic susceptibility for schizophrenia. Disease symptoms include asociality and altered social interaction. To investig...

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Autores principales: Moy, Sheryl S., Troy Ghashghaei, H., Nonneman, Randal J., Weimer, Jill M., Yokota, Yukako, Lee, Daekee, Lai, Cary, Threadgill, David W., Anton, E. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164004/
https://ncbi.nlm.nih.gov/pubmed/21547722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11689-009-9017-8
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