Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

The retinoblastoma tumor suppressor protein (pRB) can inhibit cell cycle progression and promote differentiation. pRB interacts with a variety of transcription factors, including members of the E2F and C-EBP protein families and MyoD, and can either repress or activate transcription depending on the...

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Detalles Bibliográficos
Main Authors: Sellers, William R., Novitch, Bennett G., Miyake, Satoshi, Heith, Agnieszka, Otterson, Gregory A., Kaye, Frederic J., Lassar, Andrew B., Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316399/
https://ncbi.nlm.nih.gov/pubmed/9420334
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