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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

The retinoblastoma tumor suppressor protein (pRB) can inhibit cell cycle progression and promote differentiation. pRB interacts with a variety of transcription factors, including members of the E2F and C-EBP protein families and MyoD, and can either repress or activate transcription depending on the...

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Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Sellers, William R., Novitch, Bennett G., Miyake, Satoshi, Heith, Agnieszka, Otterson, Gregory A., Kaye, Frederic J., Lassar, Andrew B., Kaelin, William G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.1.95
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