ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system

We have developed an in vitro mRNA stability system using HeLa cell cytoplasmic S100 extracts and exogenous polyadenylated RNA substrates that reproduces regulated aspects of mRNA decay. The addition of cold poly(A) competitor RNA activated both a sequence-specific deadenylase activity in the extrac...

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Xehetasun bibliografikoak

Argitaratua izan da:	Genes Dev
Egile Nagusiak:	Ford, Lance P., Watson, Janice, Keene, Jack D., Wilusz, Jeffrey
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Cold Spring Harbor Laboratory Press 1999
Gaiak:	Research Paper
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.2.188
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