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Interferon-lambda and therapy for chronic hepatitis C virus infection

Interferon (IFN)-α, a type-I IFN, is widely used to treat chronic hepatitis C virus (HCV) infection, but the broad expression of IFN-α receptors often leads to adverse reactions in many organs. Here, we examine IFN-λ, a type-III IFN, as a therapeutic alternative to IFN-α. Like IFN-α, IFN-λ also indu...

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Main Authors: Donnelly, Raymond P., Dickensheets, Harold, O'Brien, Thomas R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163738/
https://ncbi.nlm.nih.gov/pubmed/21820962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.07.002
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