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In vitro C3 Deposition on Cryptococcus Capsule Occurs Via Multiple Complement Activation Pathways

Complement can be activated via three pathways: classical, alternative, and lectin. Cryptococcus gattii and C. neoformans are closely related fungal pathogens possessing a polysaccharide capsule composed mainly of glucuronoxylomannan (GXM), which serves as a site for complement activation and deposi...

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Detalhes bibliográficos
Main Authors: Mershon-Shier, Kileen L., Vasuthasawat, Alex, Takahashi, Kazue, Morrison, Sherie L., Beenhouwer, David O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163710/
https://ncbi.nlm.nih.gov/pubmed/21723612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.06.215
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