Overexpression of SOD in Retina; Need for Increase in H(2)0(2)-Detoxifying Enzyme in Same Cellular Compartment

In retinitis pigmentosa (RP), various mutations cause rod photoreceptor cell death leading to increased oxygen levels in the outer retina, progressive oxidative damage to cones, and gradual loss of cone cell function. We have been exploring the potential of overexpressing components of the endogenou...

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Detalhes bibliográficos
Main Authors: Usui, Shinichi, Oveson, Brian C, Iwase, Takeshi, Lu, Lili, Lee, Sun Young, Jo, Young-Joon, Wu, Zhihao, Choi, Eun-Young, Samulski, Richard J., Campochiaro, Peter A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163708/
https://ncbi.nlm.nih.gov/pubmed/21736939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.06.010
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