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Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB

Assembly and activity of yeast RNA polymerase II (Pol II) preinitiation complexes (PIC) was investigated with an immobilized promoter assay and extracts made from wild-type cells and from cells containing conditional mutations in components of the Pol II machinery. We describe the following findings...

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Autors principals: Ranish, Jeffrey A., Yudkovsky, Natalya, Hahn, Steven
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316368/
https://ncbi.nlm.nih.gov/pubmed/9887099
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